Scientific Programme


28 August 2019   29 August 2019  30 August 2019  31 August 2019  1 September 2019


 

Pre-Conference workshops & sessions

Wednesday, 28 August 2019

Special Session: Latest Research from China

9:00am - 1:00pm

Part 1: Animal and Zoonotic Influenza in China  |  Part 2: Pharmaceutical research in China (with a focus on Chinese medicine)

Avian Influenza Control in China - Hualan Chen

Human Infections with Zoonotic Influenza Virus - Dayan Wang

A focus on Chinese medicine in the clinical treatment of Influenza - Bin Cao

Prediction of zoonotic influenza virus transmission and severity using biomarkers - Yuelong Shu

Seasonal Influenza vaccine policy development and implementation in China - Luzhao Feng

Pandemic risk from animal and zoonotic influenza, and national preparedness - Lei Shou

 

 

BREAK

3:00pm - 3:30pm 

WELCOME

Lance Jennings, ISIRV Chair

Vernon Lee, OPTIONS X Chair

3:30pm - 4:00pm 

Coffee Break in the Exhibit Hall

4:00pm - 5:30pm 

Opening Keynotes

Pandemic/Avian Flu through the years/risk to the future - Malik Peiris

Current state of science/future development - Kanta Subbarao [WHO Influenza Collaborating Centre, Australia]

Impact of Influenza/Pandemics - what can be done for the future?

5:30pm - 7:30pm  Welcome Reception / Poster session 1 in the Exhibit Hall

 

Thursday, 29 August 2019

8:30am - 10:00am

Plenary Session 1 - Vaccines

Challenges in Controlling Flu - Dan Jernigan [CDC, Atlanta, USA]

Universal Vaccines - Barney Graham [NIH, VRC]

10:00am- 10:30am Coffee Break in the Exhibit Hall
10:30am-12:30pm

SESSION 1

Virus Pathogenesis & Transmission Diagnosis I Vaccine Efficacy / Effectiveness I

1. Transmission of avian influenza viruses - Hui-Ling Yen [Hong Kong University]

1.  Molecular point-of-care testing for influenza in hospitals:the evidence to date - Tristan Clarke 1. Do Influenza vaccines attenuate the severity of breakthrough infections? - Mark Thompson [CDC]
 2. Pathogenesis and transmission of emerging influenza viruses - Sander Herfst [Erasmus MC, Netherlands] 2 Host response signatures and transcriptomics - Ann Falsey 2. Impact on cardiovascular outcomes - Jeff Kwong
3. Determinants of influenza virus transmission - Anice Lowen [Emory University, Atlanta, US]    
Oral Presentations (6) Oral Presentations (7) Oral Presentations (7)
12:30pm - 2:00pm

Lunch Break in Exhibit Hall / Sponsored Lunch Symposium

2:00pm - 4:00pm

SESSION 2

Diagnosis II Vaccine Efficacy/Effectiveness II Co-infection
1 Antiviral resistance [NAIs] - Larisa Gubareva [CDC] 1 2019 Southen Hemisphere Vaccine Efficacy - Sheena Sullivan 1 Vaccination against viral infections to reduce antimicrobial resistance - Padmini Srikantiah [Bill & Melinda Gates Foundation]
2 Antiviral resistance [Polymerase inhibitors] - Aeron Hurt 2 Immune responses to repeated vaccination - Annette Fox 2 Interactions between influenza and pneumococci
3 Clinical studies on immunopathogenesis - Jake Dunning 3 VE after repeated vaccination - Danuta Skowronski 3 Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms
Oral Presentations (6) Oral Presentations (6) Oral Presentations (6)
4:00 pm - 4:30 pm    Coffee Break in the Exhibit Hall
4:30pm - 6:00pm

SESSION 3

Influenza Glycobiology Treatment I Surveillance & Forecasting
1 Investigating virus-glycan interactions using novel glycan arrays - Ram Sasisekharan 1 The ‘polymerase inhibitors’ [clinical data] - Nelson Lee

1 Forecasting activity - Jeff Shaman

2 Glycan specificity of hemagglutinins - Rob de Vries 2 Polyclonal and monoclonal antibodiesfor the treatment of influenza - John Beigel [NIH] 2 Forecasting epidemics - Rob Moss
3 Role of antibody glycans in influenza immunity 3 Antiviral resistance, management aspects [esp. in immunosuppressed hosts] - Mike Ison [Northwestern University, USA] 3 Forecasting virus strains - Trevor Bedford [Fred Hutch, USA]
Oral Presentations (4) Oral Presentations (4) Oral Presentations (4)
6:00pm  - 7:30pm

Sponsored Evening Symposium

6:00pm  - 8:00pm ISIRV Epidemiology Group Session
 

Friday, 30 August 2019

8:30 am – 10:00 am 

Plenary Session 2: PISA & Virology

New Insights into Influenza Virology - Yoshi Kawaoka

10:00am – 10:30am Coffee Break in the Exhibit Hall
10:30am - 12:30pm

SESSION 4

NextGen/Universal Vaccines Treatment II Optimising Vaccine Strategies I

1 Neuraminidase vaccines - Florian Krammer [Icahn School, of Medicine, NY, USA]

1 Adjuvant therapy for severe influenza infection - Ivan Hung [University of Hong Kong]

1 Immune responses to enhanced vaccines - Andrea Sant [University of Rochester Medical Center, USA]

2 Computationally optimized broadly reactive antigen (COBRA) vaccines - Ted Ross [UGA, USA] 2 Corticosteroids - Bin Cao 2 Immune responses to enhanced vaccines/combinations (PIVOT) - Ben Cowling [University of Hong Kong]
3 T cell antigen vaccines - Sarah Gilbert [University of Oxford, UK] 3 Potential host targeted therapies in influenza - Andres Pizzorno  
Oral Presentations (6) Oral Presentations (6) Oral Presentations (6)
12:30pm - 2:00pm

Lunch Break in Exhibit Hall / Sponsored Lunch Symposium

2:00pm - 4:00pm

SESSION 5

Immune Response to Infection Optimising Vaccine Strategies II Controlled Human Infection Model (CHIM) Challenge Studies

1 T cell responses to influenza infection in humans - Katherine Kedzierska

1.Efficacy of live-attenuated vaccines - Martin Friede (WHO)

1 Human challenge with LAIV - Thushan DaSilva

2 Determinants of immune response to influenza, healing, pathology and memory - Paul Thomas [St Jude Children's Research Hospital, USA] 2 Childhood Program - Richard Pebody [Public Health England, UK] 2. Learning human immunology from live viral challenge of volunteers - Chris Chiu
3 - Immune responses to zoonotic influenza viruses in animal models - Mark Tompkins [University of Georgia, USA]   3.Infection biomarker assisted decision-making for infectious disease - Chris Woods
    4. Human Challenge
Oral Presentations (6) Oral Presentations (7) Oral Presentations (5)
4:00 pm - 4:30 pm Coffee Break in the Exhibit Hall
4:30pm - 6:00pm

SESSION 6

Cellular and Molecular Virology Avian and Zoonotic Influenza Infection Severity

1 Inhibitors targeting the RDRP - Richard Plemper

1 Clinical features of Avian influenza [H7N9] - Zhong Nan Shan (Guangzhou Institute of Respiratory Health)

1 Pandemic Severity Assessment - Carrie Reed

2 New structural insightsinto RNA synthesis by influenza polymerase - Stephan Cusack 2 Swine virus infections - Andrew S Bowman (CDC, USA) 2 Severity - Barbara Rath
3 Modulation of cellular sphingolipids during influenza infection - Hassan Zaraket (American University Beirut) 3 Clinical features of H5N1 and other NA subtypes - David Hui 3 Testing Pre-Pandemic Vaccines - NIH VTU
4 Modulation of cellular sphingolipids during influenza infection     
Oral Presentations (3) Oral Presentations (4) Oral Presentations (5)
6:00pm  - 7:30pm

Poster Session 2

   

Saturday, 31 August 2019

8:30am - 10:00am

Plenary Session 3 - Burden of Disease

10:00am - 10:30am Coffee Break in the Exhibit Hall
10:30am - 12:30pm

SESSION 7

Host-Pathogen Interactions Influenza in the Tropics Policy Perspectives for the Prevention and Control of Seasonal Influenza

1 Immunity to influenza in dirty mice - Ryan Langlios [University of Minnesota, USA]

1 Flu in tropics - Lance Jennings

1 Effectiveness of influenza vaccination in different populations - Brendan Flannery [CDC]

2 Obesity as a risk factor in influenza virus infection - Stacey Schultz-Cherry [St Jude Children's Research Hospital, USA] 2 Seasonality or Waning of Protection - Alex Cook 2 Effectiveness of neuraminidase inhibitor treatment/effectiveness of antivirals - Jonathan Nguyen Van Tam
3 Host Factors that inpact influenza polymerase activity - Wendy Barclay [Imperial College London, UK] 3 Timing of vaccination - Mark Chen 3 Policy considerations for the prevention and control of seasonal influenza - High Income Country - Kong Insik
Oral Presentations (4) Oral Presentations (4) 4 Policy considerations for the prevention and control of seasonal influenza - Middle Income Country
   

5 Panel discussion on overcoming challenges for implementation of prevention and control of seasonal influenza -

Low Income country - Ly Sovann | Middle Income country - Chong Chee Kheong

 

12:30pm - 2:00pm

Lunch Break in Exhibit Hall / Sponsored Lunch Symposium

2:00pm - 3:30pm

SESSION 8

Viral Replication Special Populations - Clinical Aspects Policy Perspectives for Pandemic Influenza Preparedness & Response

1 Regulation of virus replication -  Andrew Mehle (University of Wisconsin)

1 Pediatrics [e.g. mortality, neurologic complications, antiviral use] - Andrew Pavla (University of Utah)

1: Evidence on effectiveness of non-pharmaceutical measures

2 Inhibitors targeting the Rdp - Richard Plemper 2 Pregnant women - Marta Nunes 2: Policy considerations for pandemic preparedness and response planning - High Income country Vernon Lee (MOH, Singapore)
3 Viral Mini RNAs -  Aartjan te Velthuis 3 Elderly, including vaccination - Melissa Andrew 3: Policy considerations for pandemic preparedness and response planning -  Middle Income country Supamit Chunsuttiowat (Thailand)
Oral Presentations (5) Oral Presentations (5) Panel discussion on overcoming challenges for pandemic preparedness planning
3:30 pm - 4:00 pm Coffee Break in the Exhibit Hall
4:00pm - 5:30pm

SESSION 9

Influenza Evolution & Human Ecology Critical Influenza Illness Disease burden, Impact and Severity

1 Experimental and computational approaches to understanding influenza evolution - Jesse Bloom [Fred Hutch, USA]

1 The critically ill [e.g. management, ECMO] - Steve Webb

1 Burden and policy - Cheryl Cohen

2 Emergence and evolution of zoonotic influenza viruses - Martha Nelson 2 Cardiovascular complications (eg, MI, myocarditis, stroke) 2.Global hospitalization burden - Danielle Iuliano
3 Evolution of seasonal influenza viruses - Colin Russell 3 Neurological complications - Tim Uyeki [CDC]  
Oral Presentations (4) Oral Presentations (4) Oral Presentations (5)
5:30pm - 7:00pm

Poster Session 3

7:30pm Conference Gala Dinner at the Flower Dome - Gardens by the Bay (ticketed event)

Sunday, 1 September 2019

8:30am - 10:30am

SESSION 10

Non-Human Influenza Viruses Non-Pharmaceutical Interventions Imprinting, Sero-epidemiology, Age Profile Differences

1 Swine influenza - Kristien van Reeth

1 Aerosol transmission and the use of face masks - Lewis Radonovich

1: Epidemiologic signs of imprinting - Sarah Cobey

2 Canine influenza - Colin Parrish [Cornell University College of Veterinary Medicine, USA] 2 The contagious phenotype for influenza - Donald Milton

2: Mechanisms for imprinting - Scott Hensley

3 Avian influenza - Thijs Kulken (Erasmus) 3 Community and country-level NPIs - what works and what does not - Simon Cauchemez 3: Sero-epidemiology - Adam Kucharski
Oral Presentations (6) Oral Presentations (6) Oral Presentations (6)
10:30am - 11:00am

Coffee Break in Exhibit Hall

11:00am - 1:00pm

SESSION 11

Emerging Influenza Viruses Vaccines Epidemiology and Transmission

1 Zoonotic influenza/ One health - Ab Osterhaus

1 Immune imprinting

1 Hospital outbreaks - Paul Tambyah

2 Emergence of swine influenza in Australia - Vijay Dhanasekaran 2 Vaccination Immunocompromised - Deepali Kumar 2 Deep sequencing and mapping chains of transmission - Sebastian Maurer Stroh
3 Emergence of avian influenza viruses - Maria Zhu [Hong Kong University] 3 On waning and boosting: is there a sweet spot for influenza vaccinationstrategies in the tropics - Barnaby Young  
4 Bat influenza viruses - Martin Schwemmle    
Oral Presentations (5) Oral Presentations (6) Oral Presentations (6)
1:00pm - 1:30pm Refreshment Break
1:30pm +

Closing Plenary Session

Future Response & WHO Initiatives - Sylvie Brand, WHO

Future of Pandemic Preparedness Planning and How Scientific Evidence Can Be Used For Policy Making - Gabriel Leung

End of Conference