Scientific Programme

28 August 2019   29 August 2019  30 August 2019  31 August 2019  1 September 2019


SEE Pre-Conference workshops & sessions

Wednesday, 28 August 2019

Special Session: Latest Research from China


Special Session WELCOME

China CDC Representative TBC


Part 1: Animal and Zoonotic Influenza in China 

9:15am - 9:45am

9:45am - 10:15am

10:15am - 10:45am

10:45am - 11:15am

Avian Influenza Control in China - Hualan Chen | Chinese Academy of Agricultural Sciences

Human Infections with Zoonotic Influenza Virus - Dayan Wang | Chinese National Influenza Centre

Pandemic Risk from Animal and Zoonotic Influenza, and National Preparedness - Lei Zhou | Public Health Emergency Centre, China CDC

Seasonal Influenza Vaccine Policy Development and Implementation in China - Luzhao Feng | Division of Infectious Diseases, China CDC

11:15am - 11:30am

Refreshment Break


Part 2: Pharmaceutical Research in China (with a focus on Chinese Medicine)

11:30am - 12:00pm


12:00pm - 12:30pm

12:30pm - 1:00pm

Adjuvant Use of Traditional Chinese Medicine in Influenza and Pneumonia - Bin Cao | National Clinical Research Centre for Respiratory Diseases, People's Republic of China

Repress Antiviral Genes Stat 1/2 in Avian Influenza Infection - Cheng Yu Jiang | Chinese Academy of Medical Sciences

Prediction of Zoonotic Influenza Virus Transmission and Clinic Severity Using Biomarkers - Yuelong Shu | School of Public Health,Sun Yat-Sen University

1:00pm - 3:00pm


3:00pm - 3:30pm 


Lance Jennings, ISIRV Chair

Vernon Lee, OPTIONS X Chair

Dr Lam Pin Min, Senior Minister of State for Health and Transport

3:30pm - 4:00pm 

Coffee Break in the Exhibit Hall

4:00pm - 5:30pm 

Opening Keynotes

Pandemic/Avian Flu through the years/risk to the future - Malik Peiris

Current state of science/future development - Kanta Subbarao [WHO Influenza Collaborating Centre, Australia]

Impact of Influenza/Pandemics - what can be done for the future? - Mike Ryan

5:30pm - 7:30pm 

Welcome Reception / Poster session 1 in the Exhibit Hall


Thursday, 29 August 2019

8:30am - 10:00am

Plenary Session 1 - Vaccines

Challenges in Controlling Flu - Dan Jernigan [CDC, Atlanta, USA]

Design Options for Universal Influenza Vaccines - Barney Graham [NIH, VRC]

10:00am-10:30am Coffee Break in the Exhibit Hall


Virus Pathogenesis & Transmission Clinical I Vaccine Efficacy / Effectiveness I

1. Influenza Transmission in Experimental and Field Settings - Hui-Ling Yen [Hong Kong University]

1. Rapid Diagnosis of Influenza - Maria Zambon [Public Health England] 1. Do Influenza Vaccines Attenuate the Severity of Breakthrough Infections? - Mark Thompson [CDC]
2. Pathogenesis and Transmission of Emerging Influenza Viruses - Sander Herfst [Erasmus MC, Netherlands] 2 Shifting the Diagnostic Paradigm from Pathogen to Host - Ann Falsey 2. Impact on cardiovascular outcomes - Jeff Kwong
3. Implications of Incomplete Viral Genomes for Influenza A Virus- Anice Lowen [Emory University, Atlanta, US] 3.Innovation in Pandemic Influenza Response - Rick Bright  
Oral Presentations (2) Oral Presentations (2) Oral Presentations (4)

Lunch Break in Exhibit Hall 

Sponsored Lunch Symposium - Sanofi Pasteur



Clinical II Vaccine Efficacy/Effectiveness II Co-infection
1 Neuraminidase Inhibitors: In Pursuit of Laboratory Correlates of Clinically Relevant Resistance- Larisa Gubareva [CDC] 1 Explaining differences in vaccine effectiveness and virus circulation in the Southern Hemisphere, 2019 - Sheena Sullivan 1 Vaccination Against Viral Infections to Reduce Antimicrobial Resistance - Padmini Srikantiah [Bill & Melinda Gates Foundation]
2 Antiviral resistance [Polymerase inhibitors] - Aeron Hurt 2 Immune Responses to Repeated Vaccination - Annette Fox 2 Bacterial Interactions: The Role of Influenza in the Epidemiology of Pneumonia - Pej Rohani
3 Clinical Studies on Immunopathogenesis - Jake Dunning 3 Variable Effects of annually repeated inflenza vaccination:evidence, mechanisms and implications - Danuta Skowronski 3 Management of co-infection in Emerging Influenza - Insights from the WHO New Standard Influenza Clinical Management Guidance - Nahoko Shindo
Oral Presentations (6) Oral Presentations (6) Oral Presentations (6)
4:00pm - 4:30pm    Coffee Break in the Exhibit Hall
4:30pm - 6:00pm


Influenza Glycobiology Clinical III Surveillance & Forecasting
1 Evolution of Virus-Glycan Interactions - Andrew Thompson 1 Inhibiting Viral Polymerase in Treating Influenza: Clinical Updates - Nelson Lee

1 Forecasting Seasonal Influenza Activity - Jeff Shaman

2 N-Glycolylneuraminic Acid as a Recptor for Influenza A Viruses - Rob de Vries 2 Polyclonal and Monoclonal Antibodies for the Treatment of Influenza - John Beigel [NIH] 2 Building a Forecasting Capability for Australian Public Health - Rob Moss
3 Defining Correlates of Immunity Against Influenza Using Systems Serology - Galit Alter [ Ragon Institute ] 3 Antiviral Resistance, Management Aspects [esp. in immunosuppressed hosts] - Mike Ison [Northwestern University, USA] 3 Forecasting virus strains - Trevor Bedford [Fred Hutch, USA]
Oral Presentations (4) Oral Presentations (4) Oral Presentations (4)

6:00pm - 7:30pm

Sponsored Evening Symposium - Hoffman-Roche

6:00pm - 8:00pm ISIRV Epidemiology Group Session

Friday, 30 August 2019


Plenary Session 2: PISA & Virology

Combination Influenza Therapy: Concept to Clinical Reality - Fred Hayden

Challenges in Influenza - Yoshi Kawaoka

10:00am-10:30am Coffee Break in the Exhibit Hall


NextGen/Universal Vaccines Clinical IV Optimising Vaccine Strategies I

1 The Influenza Virus Neuraminidase as a Vaccine Target - Florian Krammer [Icahn School of Medicine USA]

1 Adjuvant Therapy for Severe Influenza Infection - Ivan Hung [University of Hong Kong]

1 Strategies to Enhance local Protective Influenza-Specific Immunity in the Respiratory Tract - Andrea Sant [University of Rochester Medical Center, USA]

2 Next-Generation Broadly Reactive Influenza Vaccines - Ted Ross [UGA, USA] 2 Adjuvant Use of Corticostroids in Influenza and Pneumonia - Bin Cao 2 Comparitive Immunogenicity of Enhanced Influenza Vaccines in Older Adults in Hong Kong: A Randomized Controlled Trial (PIVOT) - Ben Cowling [University of Hong Kong]
3 T cell Vaccines Against Influenza - Sarah Gilbert [University of Oxford, UK] 3 Potential Host-targeted Therapies in Influenza - Andres Pizzorno  
Oral Presentations (5) Oral Presentations (5) Oral Presentations (6)

Lunch Break in Exhibit Hall

Sponsored Lunch Symposium - Seqirus



Immune Response to Infection Special Populations - Clinical Aspects Optimising Vaccine Strategies II

1 Human CD8+ T cell cross-reactivity across Influenza A,B and C Viruses - Katherine Kedzierska

1.Impact of Influenza Vaccination During Pregnancy on the Mother, Fetus and Infant- Marta Nunes

1 Efficacy of live-attenuated vaccines - Martin Friede [WHO]

2 How the Host Response Determines Disease Outcome After Influenza Virus Infection- Paul Thomas [St Jude Children's Research Hospital, USA] 2 Influenza and Older Adults: Farilty, Function and Healthy Ageing - Melissa Andrew 2. Influenza Vaccination of Children - What Have We Learnt? - Richard Pebody
3 - Immune Responses to Zoonotic Influenza Viruses in Animal Models - Mark Tompkins [University of Georgia, USA] 3. Influenza in Children: Challenges and Unanswered Questions- Andrew Pavia [University of Utah]  
Oral Presentations (6) Oral Presentations (5) Oral Presentations (6)
4:00pm-4:30pm Coffee Break in the Exhibit Hall


Cellular and Molecular Virology Avian and Zoonotic Influenza Infection Severity

1 Next Generation Orally Efficacious Influenza Drug Candidate with High Genetic Resistance Barrier - Richard Plemper

1 Lessons and Experience of Clinical Diagnosis and Treatment on Avian Influenza Cases in Guangzhou, China - Zhong Nan Shan (Guangzhou Institute of Respiratory Health)

1 Pandemic Severity Assessment - Carrie Reed

2 Structural Snapshots of Actively Transcribing Influenza Polymerase - Stephan Cusack 2 Zoonotic Transmissions of Influenza A Viruses at Agricultural Fairs - Andrew S Bowman (Ohio State University) 2 Disease Severity in Influenza and Other Respiratory Viral Infections - Barbara Rath
3 The Interplay Between Influenza and Cellular Sphingolipids - Hassan Zaraket (American University Beirut) 3 Clinical features of H5N1 and other NA subtypes - David Hui [HK] 3 The FLU CATs Study - Validation of Triage Tools for Use Across a National Healthcare System During Surge in Healthcare Demand Due to Pandemic Influenza - Calum Semple [University of Liverpool, UK]
Oral Presentations (2) Oral Presentations (2) Oral Presentations (2)

Poster Session 2


Saturday, 31 August 2019


Plenary Session 3 - WHO Vision and Approaches

Global Influenza Strategy: Where We Want To Be In a Decade - Ann Moen

Pandemic Influenza Preparedness - 10 Years After Pandemic H1N1 2009 - Wenqing Zhang

Measuring Influenza Severity: Where We Are and Where We Will Go - Katelijn Vandemaele

10:00am-10:30am Coffee Break in the Exhibit Hall


Host-Pathogen Interactions Influenza in the Tropics Policy Perspectives for the Prevention and Control of Seasonal Influenza

1 Immunity to Influenza in Dirty Mice - Ryan Langlios [University of Minnesota, USA]

1 Flu in tropics - Lance Jennings

1 Effectiveness of Influenza Vaccination in Different Populations - Brendan Flannery [CDC]

2 Obesity as a risk factor in influenza virus infection - Stacey Schultz-Cherry [St Jude Children's Research Hospital, USA] 2 'Seasonality' of Influenza in the Tropics Due to Waning of Protection - Alex Cook 2 Rational Policy for Neuraminidase Inhibitors - Jonathan Nguyen Van Tam
3 ANP32 Proteins:Host Factors That Impact Influenza Virus Polymerase Activity and Host Range - Wendy Barclay [Imperial College London, UK] 3 Monitoring Influenza Activity and Burden in the Tropics - Mark Chen 3 Policy considerations for the Prevention and Control of Seasonal Influenza - High Income Country - Kong Insik
Oral Presentations (5) Oral Presentations (5) 4 Evidence Neede to Accelerate Influenza Vaccine Introduction into National Immunisation Programme in China -  Middle Income Country: Hongjie Yu

5 Panel discussion on overcoming challenges for implementation of prevention and control of seasonal influenza -

Low Income country - Seng Heng [Cambodia] | Middle Income country - Chong Chee Kheong [Malaysia]


12:30pm - 2:00pm

Lunch Break in Exhibit Hall

Sponsored Lunch Symposium - GSK

2:00pm - 3:30pm


Viral Replication Policy Perspectives for Pandemic Influenza Preparedness & Response Controlled Human Infection Model (CHIM) Challenge Studies

1 How Antiviral Proteins Can Stimulate Influenza Virus Replication-  Andrew Mehle (University of Wisconsin)

1 Non-Pharmaceutical Public Health Measures for Mitigating the Risk and Imapct of Epidemic and Pandemic Influenza - Ben Cowling (University of Hong Kong)

1: Human Challenge With LAIV - Thushan De Silva

2 Visualizing Influenza Virus Assembly - Seema Lakdawala 2 Policy Considerations for Pandemic Preparedness and Response Planning - High Income Country - Vernon Lee (MOH, Singapore) 2: Mucosal Immunity in Pathogenesis and Protection Against Human Influenza Infection Challenge -  Chris Chiu (UK)
3 Mini Viral RNAs: Consequences of RNA Structure for Genome Replication and Innate Immune Sensing -  David Bauer (University of Oxford) 3 Policy considerations for pandemic preparedness and response planning -  Middle Income country - Supamit Chunsuttiowat (Thailand) 3: Infection Biomarker Assisted Decision-Making for Infectious Disease - Chris Woods (USA)
Oral Presentations (2)

Panel Discussion: Overcoming Challenges for Pandemic Preparedness Planning

Low Income Country: Seng Heng (Cambodia)

Middle Income Country: Chong Chee Kheong (Malaysia)

Oral Presentations (2)
3:30pm - 4:00pm Coffee Break in the Exhibit Hall
4:00pm - 5:30pm


Influenza Evolution & Human Ecology Critical Influenza Illness Disease burden, Impact and Severity

1 Mapping Selection on Influenza Virus From Polyclonal Human Serum - Jesse Bloom [Fred Hutch, USA]

1 REMAP-CAP: A Platform Trial to Advance Knowledge of Optimal Treatment for Critically Ill Patients with Influenza - Steve Webb

1 Influenza Burden and Links to Policy- Building the Pyramid - Cheryl Cohen

2 Influenza in the Age of Mammals - Martha Nelson 2 Neurological Complications Associated with Influenza - Tim Uyeki (CDC) 2.Global Estimates of Influenza-Associated Respiratory Hospitalization from the InfluEnza BurdEn, Global Project (IcEBErG) - Danielle Iuliano
3 Evolution of Seasonal Influenza Viruses - Colin Russell 3 Cardiovascular Complications - William Fischer (University of North Carolina)  
Oral Presentations (2) Oral Presentations (2) Oral Presentations (4)
5:30pm - 7:00pm

Poster Session 3

7:30pm Conference Gala Dinner at the Flower Dome - Gardens by the Bay (ticketed event)

Sunday, 1 September 2019

8:30am - 10:30am


Non-Human Influenza Viruses Non-Pharmaceutical Interventions Imprinting, Sero-epidemiology, Age Profile Differences

1 Ten Years After the 2009 'Swine Flu' pandemic: A Perspective from a Veterinary Biomedical Researcherv- Kristien van Reeth

1 Contagious Phenotypes of Influenza Virus Infection - Donald Milton

1 Epidemiological Consequences of Immune Memory - Sarah Cobey

2 The Emergence, Epidemiology and Evolution of the H3N8 and H3N2 Canine Influenza Virus- Colin Parrish [Cornell University College of Veterinary Medicine, USA] 2 Spread of Pandemic Influenza in US Communities in 1920 and 2009: What Changed in the Last Century - Simon Cauchemez

2 Influenza in Context: Insights Into Universal Vaccination Against Influenza - Patrick Wilson

3 Avian influenza - Thijs Kulken (Erasmus)   3 Using Serological Data to Reconstruct Historical Influenza Dynamics - Adam Kucharski
Oral Presentations (5) Oral Presentations (6) Oral Presentations (5)
10:30am - 11:00am

Coffee Break in Exhibit Hall

11:00am - 1:00pm


Emerging Influenza Viruses Vaccines Epidemiology and Transmission Dynamics

1 Fighting Influenza from a One Health Perspective - Ab Osterhaus

1 Influenza Vaccination of the Immunocompromised - Deepali Kumar

1 Healthcare Outbreaks of Influenza - Paul Tambyah

2 Emergence of swine influenza in Australia - Vijay Dhanasekaran 2 On Waning and Boosting: Is There a Sweet Spot for Influenza Vaccination Strategies in the Tropics - Barnaby Young 2 Deep Sequencing and Mapping Chains of Transmission - Sebastian Maurer Stroh
3 Emergence of Avian Influenza Viruses in Asia - Maria Zhu [Hong Kong University]    
4 Reverse Genetic Analysis of Bat Influenza Viruses: A Journey Full of Surprises - Martin Schwemmle    
Oral Presentations (3) Oral Presentations (6) Oral Presentations (6)
1:00pm-1:30pm Refreshment Break
1:30pm +

Closing Plenary Session

Future of Pandemic Preparedness Planning and How Scientific Evidence Can Be Used For Policy Making - Gabriel Leung

The Future of Influenza Vaccines - Arnold Monto

Future Response & WHO Initiatives - Sylvie Brand, WHO